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South East company wins blood freezing research funding

19 February 2010
Researchers from a Hampshire company have commenced work investigating whether it is possible to freeze dry red blood cells, which, if successful, could lead to improvements in clinical usage.

Winchester-based Biopharma Technology Limited (BTL) will work with Professor Nigel Slater from the University of Cambridge's Department of Biotechnology and Chemical Engineering on the project.

The research will focus on the identification and testing of materials that could protect blood cells during the freeze drying process.

Building on previous investigation by Cambridge's Andrew Lynch, researchers hope to be able to increase the level of sugar within cells which it is hoped will ensure they can be freeze dried without damage.

Professor Slater added that combining BTL's lyophilisation experience with the Cambridge researchers' biostabilisation technology "presents an ideal opportunity to develop additional formulation and storage protocols and has the potential to deliver near term clinical benefits in the management and therapeutic use of valuable donor materials".

BTL was established in 1997 and works with companies and research programmes worldwide to develop freeze drying techniques, from pre-formulation to production on varying scales and the analysis of end products.

"If we are successful with red blood cells which are really fragile, then it opens up the possibility of creating a platform for freeze drying therapeutic cells enabling a wider range of products and applications," said Kevin Ward, Director of Research and Development at BTL.

Expected to last six months, the study has been awarded funding by the Technology Strategy Board, a non-departmental body set up by the government which promotes collaboration in technology-driven innovation.ADNFCR-1584-ID-19626188-ADNFCR

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